Curcuma longa can prevent, or lower the gravity of, cytokine storms

Curcumin in Turmeric can prevent, or lower the gravity of, cytokine storms, the leading cause of death from Covid-19.

Potential use of turmeric in COVID-19

Quote: Curcumin has been found to attenuate virus-induced lung tissue injury by inhibiting the production of inflammatory cytokines... therefore, it might play a similar role in protecting against lung injury associated with COVID-19."

Google: Potential Turmeric COVID-19

Quote: Collectively, curcumin can modulate the events of SARS-CoV-2 cellular entry, their replication, and molecular cascade manifesting pathophysiological consequences of COVID-19. ...previous experimental evidences indicating its efficacy in respiratory ailments (including influenza and other coronavirus infections), inflammatory disorders, and coagulopathy, promotes its candidature as a drug in the treatment of COVID-19."

Curcumin: a Wonder Drug as a Preventive Measure for COVID19 Management - In line with the growing evidences of therapeutic properties of the curcumin, here we propose a hypothetical treatment strategy of using curcumin as (1) potential inhibitory agent blocking the host viral interaction (viral spike protein—ACE2 receptor) at an entry site in humans and (2) as an attenuator via modulating the proinflammatory effects of Angiotensin II-AT1 receptor-signalling pathways reducing respiratory distress in the treatment of COVID19.

Google: Curcumin Wonder Drug

References:

Ammon, Hermann P. T.; Wahl, Martin A. , (1991), Pharmacology of Curcuma longa, Planta Med 1991; 57(1): 1-7, DOI: 10.1055/s-2006-960004

Bedir, Erdal; Abou-Gazar, Hassan; Ngwendson, Julius Ngunde; Khan, Ikhlas Ahmad (2003), Eurycomaoside: A New Quassinoid-Type Glycoside from the Roots of Eurycoma longifolia, Chemical and Pharmaceutical Bulletin, Volume 51, Issue 11, Pages 1301-1303

Bhat, Rajeev; Karim, A.A. (2010), Tongkat Ali (Eurycoma longifolia Jack): A review on its ethnobotany and pharmacological importance, Fitoterapia, Volume 81, Issue 7, Pages 669-679

Bin Mohd Tambi M.I.; Imran M.K. (2010), Eurycoma longifolia Jack in managing idiopathic male infertility , Asian Journal of Andrology, Volume 12 Pages 376-380, https://doi.org/10.1038/aja.2010.7

Chen Y, Phang WM, Mu AK, Chan CK, Low BS, Sasidharan S, Chan KL. (2015), Decreased expression of alpha-2-HS glycoprotein in the sera of rats treated with Eurycoma longifolia extract Frontiers in Pharmacology, Vol 6 Page 211

Faisal, Ghasak G; Najmuldeen, Ghazi F; Abllah, Zurainie; Radeef, Ali S (2017), The Cholesterol Lowering Effects of Eurycoma longifolia Jack (Tongkat Ali) Root Extract in Male Rats. Makara Journal of Health Research (MJHR), Vol 21, No 1

George A.; Henkel R. (2014), Phytoandrogenic properties of Eurycoma longifolia as natural alternative to testosterone replacement therapy, Andrologia, Volume 46, Pages 708-721, https://doi.org/10.1111/and.12214

George A, Udani J, Abidin NZ, Yusof A. (2018). Efficacy and safety of Eurycoma longifolia (Physta®) water extract plus multivitamins on quality of life, mood and stress: a randomized placebo-controlled and parallel study. Food Nutrition Resources, Vol 62.

GG, Faisal; SM, Zakaria; GF, Najmuldeen (2015), In Vitro Antibacterial Activity of Eurycoma Longifolia Jack (Tongkat Ali) Root Extract, International Medical Journal of Malaysia, Volume 14, No. 1

Hashiguchi, Akiko; Thawtar, May San; Duangsodsri, Teerarat; Kusano, Miyako; Watanabe, Kazuo N. (2022), Biofunctional properties and plant physiology of Kaempferia spp.: Status and trends, Journal of Functional Foods Volume 92

Hirsh, Steven; Huber, Luke; Stein,Richard; Schmid,Kira; Swick, Andrew; Joyal, Steven (2018), An open label study to evaluate the effect of Kaempferia parviflora in support of erectile function and male sexual health among overall healthy males 50–70, Federation of American Societies for Expiremental Biology, Volume 31, Issue S1 Special Issue: Experimental Biology 2017 Meeting Abstracts, https://doi.org/10.1096/fasebj.31.1_supplement.636.1

Horigome S, Yoshida I, Ito S, et al. (2015), Inhibitory effects of Kaempferia parviflora extract on monocyte adhesion and cellular reactive oxygen species production in human umbilical vein endothelial cells, European Journal of Nutrition, doi:10.1007/s00394-015-1141-5.

Kim, Mi-Bo; Kim, Taeyoon; Kim, Changhee; Hwang, Jae-Kwan (2018), Standardized Kaempferia parviflora Extract Enhances Exercise Performance Through Activation of Mitochondrial Biogenesis, Journal of Medicinal Food, Vol. 21, No. 1

Klinjan, Preeyaporn; Mungkornasawakul, Pitchaya; Tragoolpua, Yingmanee; Sangthong, Padchanee (2021) Cytotoxicity and anti-herpes simplex virus type-1 activity of Kaempferia parviflora extract, APST, Vol. 26 No. 03

Kobayashi, Hiroko; Suzuki, Ryo; Sato, Kei; Ogami, Takatoshi; Tomozawa, Hiroshi; Tsubata, Masahito; Ichinose, Koji; Aburada, Masaki; Ochiai, Wataru; Sugiyama, Kiyoshi; Shimada, Tsutomu (2017), Effect of Kaempferia parviflora extract on knee osteoarthritis, Journal of Natural Medicines Volume 72, Pages 136–144

Kocaadam, Betül; ?anlier, Nevin, (2015), Curcumin, an active component of turmeric (Curcuma longa), and its effects on health, Critical Reviews in Food Science and Nutrition Volume 57, 2017 - Issue 13, https://doi.org/10.1080/10408398.2015.1077195

Kusirisin, W.; Srichairatanakool, S.; Lerttrakarnnon, P.; Lailerd, N.; Suttajit, M.; Jaikang, C.; Chaiyasut, C. (2009), Antioxidative activity, polyphenolic content and anti-glycation effect of some Thai medicinal plants traditionally used in diabetic patients, Journal of Medicinal Chemistry (Los Angeles), Volume 5 (2) Pages139-147, 10.2174/157340609787582918

Leardkamolkarn V, Tiamyuyen S, Sripanidkulchai BO. (2009), Pharmacological activity of Kaempferia parviflora extract against human bile duct cancer cell lines, Asian Pacific Journal of Cancer Prevention, Volume10, Pages 695–698

Lee, Man-Hyo; Sung, Hwa-Jung; Kwon, Chong Suk; Sohn, Ho-Yong (2018), Anti-coagulation and Anti-platelet Aggregation Activities of Black Ginger (Kaempferia parviflora), Journal of Life Science, Volume 28 Issue 9, Pages.1068-1075

Selvam, R.; Subramanian, Lalitha; Gayathri, R. ; Angayarkanni, N. , (1995), The anti-oxidant activity of turmeric (Curcuma longa)Journal of Ethnopharmacology, Volume 47, Issue 2, 7 July 1995, Pages 59-67

TONGKATALI.ORG - Medan - North Sumatra - Indonesia